yahuasca is all over the news these days. But how much do you actually know about ayahuasca’s effects on the brain, body and mind? Did you know that ayahuasca triggers “neuroplasticity” or the brain’s ability to adapt and transform? What this neural adaptability means to the therapeutic potential of ayahuasca is not fully clear, but there is evidence to show that certain types of neuroplasticity are important for the journey of healing mental illness.

The experience of ayahuasca is nothing short of extraordinary and in many ways it transcends the instruments of science and, some would argue, the material universe. Ayahuasca drinkers typically draw upon spiritual traditions to guide their visionary journeys. At the same time, it’s becoming more and more obvious that separating spirit from science does not appear to be the best way forward.

Because, science has enabled us to understand the short-term and long-term effects of ayahuasca in powerful ways. Neuroscientific research suggests that ayahuasca, when used in the correct settings, may be able to relieve trauma and heal deep emotional wounds – the domain of spiritual life. This short scene from documentary The Jungle Prescription explains more:


Two molecules in ayahuasca have been shown to grow new brain neurons in laboratory experiments.

DMT has been shown to raise Brain-Derived Neurotrophic Factor (BDNF) levels in the brain. Common anti-depressant medications also raise BDNF levels, but you need to take them every day for two weeks to begin to experience an increase. DMT increases BDNF levels immediately and sustains an increase for up to 2 weeks from one single dose. This is often referred to as the psychedelic “after glow” effect. Interestingly, Harmine and harmaline have also been shown to increase BDNF levels. In addition, harmine has also been shown to have anti-anxiety properties (i.e. anxiolytic effects).

Connected to the spiritual experiences of ayahuasca are profound visionary encounters. People report seeing complex geometric designs, beautiful or grotesque scenes, unfamiliar landscapes, jewelled palaces, and spirits. Kahpi teacher and neuroscientists, Dr. Draulio de Araujo scanned the brains of experienced ayahuasca drinkers while they were having strong visions. His research showed that when people are experiencing ayahuasca visions, parts of brain associated with memory, emotion, intention and seeing, were activated. He explains more in this video:

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